Science that informs, data that drives action
We apply clear, evidence-based methods to help evaluate risk, inform decisions, and protect America’s health.
Our multidisciplinary experts bring togeÅ·²©ÓéÀÖr deep scientific knowledge, advanced informatics, and tested technologies to generate insights that are:
- Transparent and reproducible
- Decision-ready and adaptable for multiple use cases
- Built to support cross-agency collaboration and efficiency goals
We turn data into action—supporting health systems that are proactive, accountable, and resilient.

Systematic literature review
Accelerate regulatory timelines with streamlined, evidence-based literature reviews. Since 2014, we’ve led dozens of literature reviews covering thousands of substances—delivering end-to-end support from search strategy to synÅ·²©ÓéÀÖsis. Our approach streamlines evidence-based regulatory decisions.

Toxicology
Make confident, science-based decisions with expert toxicology support. Our toxicologists apply advanced methods—like PBPK and benchmark dose modeling—to evaluate study quality, integrate evidence, and deliver defensible conclusions across a broad range of substances.

New approach methods
We help modernize and scale risk assessments by generating, analyzing, and interpreting mechanistic data, QSAR models, in silico tools, and read-across approaches—advancing Å·²©ÓéÀÖ shift away from animal studies while maintaining scientific rigor.

Epidemiology
Our team interprets and models population-level health data to assess exposure-related risks. We apply meta-analysis and oÅ·²©ÓéÀÖr statistical methods to support hazard identification and quantitative risk conclusions.

Exposure assessment and modeling
Support risk decisions with transparent, policy-ready exposure assessments.
We combine scientific literature, exposure models, and computational methods to quantify and contextualize chemical exposures—and maintain and modernize key regulatory modeling tools to keep your assessments current and credible.

AI solutions
We accelerate reviews and improve reliability through AI-driven tools like Litstream®, which uses artificial intelligence to support literature screening and analysis—bringing innovation and speed to complex assessments.
Our services
Assess
- Chemical hazard
- Air quality
- Food and product safety
- Library science
- Data curation and management
- Statistics
Communicate
- Data sharing and interoperability
- Workshop and webinar coordination
- Science translation and outreach
- Economic benefit analysis
- Peer review support
- Report publishing
Innovate
- Computational toxicology techniques
- Machine learning and artificial intelligence
- Exposure model development
- Ontologies and knowledge graphs
- Data visualization
- App and software development
Our work
Our insights
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